increased gastrointestinal tumor incidence_Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>

http://metadb.riken.jp/0010279I129S4SvJaeC57BL6C57BL6JApcMinApcCol1a1tm1CAGSirt1DsinCol1a1ApcMinCol1a1Col1a1tm1CAGSirt1DsinApc

increased gastrointestinal tumor incidence_Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<Min>|Col1a1<+>|Col1a1<tm1(CAG-Sirt1)Dsin>|Apc<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased gastrointestinal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010279

文献

http://purl.org/net/cito/citesAsAuthority

• Ron. Firestein, et.al., The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/18414679