increased skeletal tumor incidence_Nf2<tm2Gth>/Nf2<+>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)3Gth/0

http://metadb.riken.jp/0010280I129P2OlaHsd129S7SvEvBrdFVBNNf2tm2GthNf2Trp53tm1BrdTrp53TgP0Cre3Gth0Trp53tm1BrdTrp53Nf2tm2GthTgP0Cre3GthNf2

increased skeletal tumor incidence_Nf2<tm2Gth>/Nf2<+>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)3Gth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3, Gilles Thomas
  http://metadb.riken.jp/db/mgi_rdf/MGI:3047154
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• neurofibromin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97307

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf2<tm2Gth>/Nf2<+>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)3Gth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Trp53<+>|Nf2<tm2Gth>|Tg(P0-Cre)3Gth|Nf2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skeletal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010280

文献

http://purl.org/net/cito/citesAsAuthority

• Els. Robanus-Maandag, et.al., Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin., Oncogene, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15221010