increased nervous system tumor incidence_Nf2<tm2Gth>/Nf2<tm2Gth>,Ptgds<tm1.1(cre)Gvn>/Ptgds<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0010281I129P2OlaHsdFVBNNf2tm2GthNf2tm2GthPtgdstm11creGvnPtgdsTrp53tm1BrnTrp53tm1BrnNf2tm2GthPtgdstm11creGvnTrp53tm1BrnPtgds

increased nervous system tumor incidence_Nf2<tm2Gth>/Nf2<tm2Gth>,Ptgds<tm1.1(cre)Gvn>/Ptgds<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prostaglandin D2 synthase (brain)
  http://metadb.riken.jp/db/mgi_rdf/MGI:99261
• neurofibromin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97307
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf2<tm2Gth>/Nf2<tm2Gth>,Ptgds<tm1.1(cre)Gvn>/Ptgds<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nf2<tm2Gth>|Ptgds<tm1.1(cre)Gvn>|Trp53<tm1Brn>|Ptgds<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased nervous system tumor incidence
  http://purl.obolibrary.org/obo/MP_0010281

文献

http://purl.org/net/cito/citesAsAuthority

• M. Kalamarides, et.al., Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes., Oncogene, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21242963