increased mammary gland tumor incidence_Etv6<tm3(NTRK3)Sho>/Etv6<+>,Tg(Wap-cre)11738Mam/0

http://metadb.riken.jp/0010299I129S1SvC57BL6SJLEtv6tm3NTRK3ShoEtv6TgWapcre11738Mam0TgWapcre11738MamEtv6tm3NTRK3ShoEtv6

increased mammary gland tumor incidence_Etv6<tm3(NTRK3)Sho>/Etv6<+>,Tg(Wap-cre)11738Mam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 11738, Lothar Hennighausen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176164
• ets variant 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:109336

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Etv6<tm3(NTRK3)Sho>/Etv6<+>,Tg(Wap-cre)11738Mam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wap-cre)11738Mam|Etv6<tm3(NTRK3)Sho>|Etv6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Zhe. Li, et.al., ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex., Cancer cell, 2007, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/18068631