increased mammary gland tumor incidence_Eef1a1<tm1(Kras*)Arge>/Eef1a1<+>,Igf1r<tm2Arge>/Igf1r<+>,Wap<tm1(cre)Arge>/Wap<+>

http://metadb.riken.jp/0010299I129S1SvEef1a1tm1KrasArgeEef1a1Igf1rtm2ArgeIgf1rWaptm1creArgeWapEef1a1tm1KrasArgeEef1a1Waptm1creArgeWapIgf1rtm2ArgeIgf1r

increased mammary gland tumor incidence_Eef1a1<tm1(Kras*)Arge>/Eef1a1<+>,Igf1r<tm2Arge>/Igf1r<+>,Wap<tm1(cre)Arge>/Wap<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• eukaryotic translation elongation factor 1 alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096881
• whey acidic protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:98943
• insulin-like growth factor I receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96433

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eef1a1<tm1(Kras*)Arge>/Eef1a1<+>,Igf1r<tm2Arge>/Igf1r<+>,Wap<tm1(cre)Arge>/Wap<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Eef1a1<tm1(Kras*)Arge>|Eef1a1<+>|Wap<tm1(cre)Arge>|Wap<+>|Igf1r<tm2Arge>|Igf1r<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Apostolos. Klinakis, et.al., Igf1r as a therapeutic target in a mouse model of basal-like breast cancer., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19174523