increased mammary gland tumor incidence_Ccnd1<tm1Wbg>/Ccnd1<tm1Wbg>,Tg(MMTVneu)202Mul/0,Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0

http://metadb.riken.jp/0010299I129S2SvPasFVBNCcnd1tm1WbgCcnd1tm1WbgTgMMTVneu202Mul0TgtetOCcnd1T286Aluc11233Kuw0TgMMTVneu202MulCcnd1tm1WbgTgtetOCcnd1T286Aluc11233Kuw

increased mammary gland tumor incidence_Ccnd1<tm1Wbg>/Ccnd1<tm1Wbg>,Tg(MMTVneu)202Mul/0,Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 11233, Kay-Uwe Wagner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5300561
• cyclin D1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88313
• transgene insertion 202, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930203

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccnd1<tm1Wbg>/Ccnd1<tm1Wbg>,Tg(MMTVneu)202Mul/0,Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTVneu)202Mul|Ccnd1<tm1Wbg>|Tg(tetO-Ccnd1*T286A,-luc)11233Kuw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Qian. Zhang, et.al., Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression., Cancer research, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/22037875