increased mammary gland tumor incidence_Cav1<tm1Mls>/Cav1<+>,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0010299I129SvC57BL6JFVBNSJLCav1tm1MlsCav1TgMMTVPyVT634Mul0TgMMTVPyVT634MulCav1Cav1tm1Mls

increased mammary gland tumor incidence_Cav1<tm1Mls>/Cav1<+>,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594
• caveolin 1, caveolae protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:102709

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cav1<tm1Mls>/Cav1<+>,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-PyVT)634Mul|Cav1<+>|Cav1<tm1Mls>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Terence M. Williams, et.al., Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice., Molecular biology of the cell, 2003, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/12631721