increased mammary gland tumor incidence_Ddr2<tm1c(EUCOMM)Wtsi>/Ddr2<tm1c(EUCOMM)Wtsi>,Tg(KRT14-cre)1Amc/0,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0010299IC57BL6C57BL6NCBAFVBNDdr2tm1cEUCOMMWtsiDdr2tm1cEUCOMMWtsiTgKRT14cre1Amc0TgMMTVPyVT634Mul0TgKRT14cre1AmcDdr2tm1cEUCOMMWtsiTgMMTVPyVT634Mul

increased mammary gland tumor incidence_Ddr2<tm1c(EUCOMM)Wtsi>/Ddr2<tm1c(EUCOMM)Wtsi>,Tg(KRT14-cre)1Amc/0,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• discoidin domain receptor family, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345277
• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450263

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ddr2<tm1c(EUCOMM)Wtsi>/Ddr2<tm1c(EUCOMM)Wtsi>,Tg(KRT14-cre)1Amc/0,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-cre)1Amc|Ddr2<tm1c(EUCOMM)Wtsi>|Tg(MMTV-PyVT)634Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Callie A S. Corsa, et.al., The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis., Cell reports, 2016, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/27264173