increased mammary gland tumor incidence_Tg(MMTVTGFA)29Rjc/0

http://metadb.riken.jp/0010299IC57BL6DBA2TgMMTVTGFA29Rjc0TgMMTVTGFA29Rjc

increased mammary gland tumor incidence_Tg(MMTVTGFA)29Rjc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 29, Robert J Coffey
  http://metadb.riken.jp/db/mgi_rdf/MGI:3040881

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(MMTVTGFA)29Rjc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTVTGFA)29Rjc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• S A. Halter, et.al., Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-alpha. Characterization of mammary gland and skin proliferations., The American journal of pathology, 1992, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/1316084
• W J. Muller, et.al., Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice., Molecular and cellular biology, 1996, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/8816486
• R J. Coffey, et.al., Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene., Cancer research, 1994, 54
  http://rdf.ncbi.nlm.nih.gov/pubmed/8137281
• D F. Pierce, et.al., Mammary tumor suppression by transforming growth factor beta 1 transgene expression., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7753792
• Y. Matsui, et.al., Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice., Cell, 1990, 61
  http://rdf.ncbi.nlm.nih.gov/pubmed/2161707