increased mammary gland tumor incidence_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz/0

http://metadb.riken.jp/0010299IFVBNTgMMTVrtTA1Lach0TgtetOPIK3CAH1047Rluc2239Jjz0TgtetOPIK3CAH1047Rluc2239JjzTgMMTVrtTA1Lach

increased mammary gland tumor incidence_Tg(MMTV-rtTA)1Lach/0,Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2239, Jean J Zhao
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526970
• transgene insertion 1, Lewis A Chodosh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3511873

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(MMTV-rtTA)1Lach/0,Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz|Tg(MMTV-rtTA)1Lach

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010299

文献

http://purl.org/net/cito/citesAsAuthority

• Pixu. Liu, et.al., Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms., Nature medicine, 2011, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/21822287