increased stomach tumor incidence_Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0,Tg(Krt19-Wnt1)2Maos/0

http://metadb.riken.jp/0010301IC3HC57BL6TgKrt19Ptgs2Krt19Ptges8Tko0TgKrt19Wnt12Maos0TgKrt19Wnt12MaosTgKrt19Ptgs2Krt19Ptges8Tko

increased stomach tumor incidence_Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0,Tg(Krt19-Wnt1)2Maos/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Masanobu Oshima
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361182
• transgene insertion 8, Makoto Mark Taketo
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361181

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko/0,Tg(Krt19-Wnt1)2Maos/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Krt19-Wnt1)2Maos|Tg(Krt19-Ptgs2,Krt19-Ptges)8Tko

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased stomach tumor incidence
  http://purl.obolibrary.org/obo/MP_0010301

文献

http://purl.org/net/cito/citesAsAuthority

• Shin-ichi. Akaboshi, et.al., HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer., The American journal of pathology, 2009, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/19729480
• Hiroko. Oshima, et.al., Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway., Gastroenterology, 2006, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/17030179