increased mesothelioma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tsc1<tm1Djk>/Tsc1<tm1Djk>

http://metadb.riken.jp/0010309I129P2OlaHsd129S4SvJaeTrp53tm1BrnTrp53tm1BrnTsc1tm1DjkTsc1tm1DjkTrp53tm1BrnTsc1tm1Djk

increased mesothelioma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tsc1<tm1Djk>/Tsc1<tm1Djk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tuberous sclerosis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929183
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brn>/Trp53<tm1Brn>,Tsc1<tm1Djk>/Tsc1<tm1Djk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Tsc1<tm1Djk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mesothelioma incidence
  http://purl.obolibrary.org/obo/MP_0010309

文献

http://purl.org/net/cito/citesAsAuthority

• Y. Guo, et.al., Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma., Oncogene, 2014, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23851502