increased mesothelioma incidence_Cdkn2a<tm1.1Brn>/Cdkn2a<+>,Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0010309I129P2OlaHsd129S7SvEvBrdCdkn2atm11BrnCdkn2aNf2tm2GthNf2tm2GthTrp53tm1BrnTrp53tm1BrnCdkn2aNf2tm2GthCdkn2atm11BrnTrp53tm1Brn

increased mesothelioma incidence_Cdkn2a<tm1.1Brn>/Cdkn2a<+>,Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• neurofibromin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97307
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1.1Brn>/Cdkn2a<+>,Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<+>|Nf2<tm2Gth>|Cdkn2a<tm1.1Brn>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mesothelioma incidence
  http://purl.obolibrary.org/obo/MP_0010309

文献

http://purl.org/net/cito/citesAsAuthority

• Johan. Jongsma, et.al., A conditional mouse model for malignant mesothelioma., Cancer cell, 2008, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/18328429