increased neurofibroma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Gfap-cre)77.6Mvs/0

http://metadb.riken.jp/0010314I129S4SvJaeBALBcC57BL6NHsdKrastm4TyjKrasPtentm1HwuPtenTgGfapcre776Mvs0KrasKrastm4TyjPtenPtentm1HwuTgGfapcre776Mvs

increased neurofibroma incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Gfap-cre)77.6Mvs/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 77.6, Michael V Sofroniew
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838839
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<+>,Tg(Gfap-cre)77.6Mvs/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Kras<tm4Tyj>|Pten<+>|Pten<tm1Hwu>|Tg(Gfap-cre)77.6Mvs

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6NHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neurofibroma incidence
  http://purl.obolibrary.org/obo/MP_0010314

文献

http://purl.org/net/cito/citesAsAuthority

• Caroline. Gregorian, et.al., PTEN dosage is essential for neurofibroma development and malignant transformation., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19846776