increased cholangiocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0010315I129P2OlaHsd129S4SvJaeC57BL6DBAKrastm4TyjKrasTrp53tm1BrnTrp53TgAlbcre21Mgn0Krastm4TyjKrasTgAlbcre21MgnTrp53tm1BrnTrp53

increased cholangiocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Kras<+>|Tg(Alb-cre)21Mgn|Trp53<tm1Brn>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cholangiocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0010315

文献

http://purl.org/net/cito/citesAsAuthority

• Michael R. O'Dell, et.al., Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma., Cancer research, 2012, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/22266220