increased pituitary gland tumor incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Sox2<tm1.1(cre)Jpmb>/Sox2<+>

http://metadb.riken.jp/0010320I129P2OlaHsd129X1SvJC57BL6Ctnnb1tm1MmtCtnnb1Sox2tm11creJpmbSox2Sox2Ctnnb1Ctnnb1tm1MmtSox2tm11creJpmb

increased pituitary gland tumor incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Sox2<tm1.1(cre)Jpmb>/Sox2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• SRY (sex determining region Y)-box 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:98364

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Mmt>/Ctnnb1<+>,Sox2<tm1.1(cre)Jpmb>/Sox2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sox2<+>|Ctnnb1<+>|Ctnnb1<tm1Mmt>|Sox2<tm1.1(cre)Jpmb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010320

文献

http://purl.org/net/cito/citesAsAuthority

• Cynthia Lilian. Andoniadou, et.al., Sox2(+) stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential., Cell stem cell, 2013, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/24094324