increased pituitary gland tumor incidence_Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Ghrhr-cre)3242Lsk/0

http://metadb.riken.jp/0010320I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1atm12LskTgGhrhrcre3242Lsk0TgGhrhrcre3242LskPrkar1atm12Lsk

increased pituitary gland tumor incidence_Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Ghrhr-cre)3242Lsk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase, cAMP dependent regulatory, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104878
• transgene insertion 3242, Lawrence S Kirschner
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771838

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Ghrhr-cre)3242Lsk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ghrhr-cre)3242Lsk|Prkar1a<tm1.2Lsk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010320

文献

http://purl.org/net/cito/citesAsAuthority

• Zhirong. Yin, et.al., Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis., Molecular endocrinology (Baltimore, Md.), 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/17975024