increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-Nras*Q61K)#Lc/0,Tg(Tyr-rtTA)37Lc/0

http://metadb.riken.jp/0010322FVBCgCdkn2atm1RdpTgtetONrasQ61KLcTgTyrrtTA37LcCdkn2atm1RdpCdkn2atm1RdpTgtetONrasQ61KLc0TgTyrrtTA37Lc0Cdkn2atm1RdpTgTyrrtTA37LcTgtetONrasQ61KLc

increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-Nras*Q61K)#Lc/0,Tg(Tyr-rtTA)37Lc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:5818044
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 37, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039789

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(tetO-Nras*Q61K)#Lc/0,Tg(Tyr-rtTA)37Lc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Rdp>|Tg(Tyr-rtTA)37Lc|Tg(tetO-Nras*Q61K)#Lc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.Cg-Cdkn2a<tm1Rdp> Tg(tetO-Nras*Q61K)#Lc Tg(Tyr-rtTA)37Lc

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cutaneous melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010322

文献

http://purl.org/net/cito/citesAsAuthority

• Lawrence N. Kwong, et.al., Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma., Nature medicine, 2012, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/22983396