increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-NRAS*Q61K)1Bee/0

http://metadb.riken.jp/0010322I129SvC57BL6JDBA2SJLCdkn2atm1RdpCdkn2atm1RdpTgTyrNRASQ61K1Bee0TgTyrNRASQ61K1BeeCdkn2atm1Rdp

increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-NRAS*Q61K)1Bee/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Friedrich Beemann
  http://metadb.riken.jp/db/mgi_rdf/MGI:3768643
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-NRAS*Q61K)1Bee/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-NRAS*Q61K)1Bee|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * DBA/2 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cutaneous melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010322

文献

http://purl.org/net/cito/citesAsAuthority

• Olga. Shakhova, et.al., Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma., Nature cell biology, 2012, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/22772081