increased chronic lymphocytic leukemia incidence_Tg(Igh-ROR1)1Kip/0,Tg(Igh-V186.2-TCL1A)3Cro/0

http://metadb.riken.jp/0010337B6CgTgIghROR11KipTgIghV1862TCL1A3CroTgIghROR11Kip0TgIghV1862TCL1A3Cro0TgIghROR11KipTgIghV1862TCL1A3Cro

increased chronic lymphocytic leukemia incidence_Tg(Igh-ROR1)1Kip/0,Tg(Igh-V186.2-TCL1A)3Cro/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Thomas J Kipps
  http://metadb.riken.jp/db/mgi_rdf/MGI:5571365
• transgene insertion 3, Carlo M Croce
  http://metadb.riken.jp/db/mgi_rdf/MGI:3841582

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Igh-ROR1)1Kip/0,Tg(Igh-V186.2-TCL1A)3Cro/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Igh-ROR1)1Kip|Tg(Igh-V186.2-TCL1A)3Cro

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased chronic lymphocytic leukemia incidence
  http://purl.obolibrary.org/obo/MP_0010337

文献

http://purl.org/net/cito/citesAsAuthority

• George F. Widhopf, et.al., ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/24379361