increased thyroid carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<+>

http://metadb.riken.jp/0010346I129P2OlaHsdRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53Trp53tm1BrnRb1tm2BrnTrp53

increased thyroid carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Rb1<tm2Brn>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased thyroid carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0010346

文献

http://purl.org/net/cito/citesAsAuthority

• Meleeneh. Kazarian, et.al., Immune response in lung cancer mouse model mimics human anti-Hu reactivity., Journal of neuroimmunology, 2009, 217
  http://rdf.ncbi.nlm.nih.gov/pubmed/19765830
• Ralph. Meuwissen, et.al., Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model., Cancer cell, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/14522252