increased thyroid carcinoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Tg(TG-TPR/NTRK1)#Rstn/0

http://metadb.riken.jp/0010346I129S4SvJaeSorC3HC57BL6C57BL6JCdkn1btm1MlfCdkn1bTgTGTPRNTRK1Rstn0TgTGTPRNTRK1RstnCdkn1btm1MlfCdkn1b

increased thyroid carcinoma incidence_Cdkn1b<tm1Mlf>/Cdkn1b<+>,Tg(TG-TPR/NTRK1)#Rstn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565
• transgene insertion, Jay Rothstein
  http://metadb.riken.jp/db/mgi_rdf/MGI:5581424

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Mlf>/Cdkn1b<+>,Tg(TG-TPR/NTRK1)#Rstn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TG-TPR/NTRK1)#Rstn|Cdkn1b<tm1Mlf>|Cdkn1b<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C3H * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased thyroid carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0010346

文献

http://purl.org/net/cito/citesAsAuthority

• Monica. Fedele, et.al., Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice., Endocrine-related cancer, 2009, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/19261681