increased adenoma incidence_Il6st<tm1Ern>/Il6st<+>,Smad3<tm1Par>/Smad3<+>

http://metadb.riken.jp/0010383I129S1Sv129X1SvJC57BL6Il6sttm1ErnIl6stSmad3tm1ParSmad3Il6sttm1ErnSmad3tm1ParSmad3Il6st

increased adenoma incidence_Il6st<tm1Ern>/Il6st<+>,Smad3<tm1Par>/Smad3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 6 signal transducer
  http://metadb.riken.jp/db/mgi_rdf/MGI:96560
• SMAD family member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201674

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6st<tm1Ern>/Il6st<+>,Smad3<tm1Par>/Smad3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6st<tm1Ern>|Smad3<tm1Par>|Smad3<+>|Il6st<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased adenoma incidence
  http://purl.obolibrary.org/obo/MP_0010383

文献

http://purl.org/net/cito/citesAsAuthority

• Brendan J. Jenkins, et.al., Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling., Nature medicine, 2005, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/16041381