increased adenoma incidence_Il6st<tm1Ern>/Il6st<tm1Ern>

http://metadb.riken.jp/0010383I129S1SvC57BL6Il6sttm1ErnIl6sttm1ErnIl6sttm1Ern

increased adenoma incidence_Il6st<tm1Ern>/Il6st<tm1Ern>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 6 signal transducer
  http://metadb.riken.jp/db/mgi_rdf/MGI:96560

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6st<tm1Ern>/Il6st<tm1Ern>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6st<tm1Ern>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased adenoma incidence
  http://purl.obolibrary.org/obo/MP_0010383

文献

http://purl.org/net/cito/citesAsAuthority

• Niall C. Tebbutt, et.al., Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice., Nature medicine, 2002, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/12219085
• Louise M. Judd, et.al., Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130., Gastroenterology, 2004, 126
  http://rdf.ncbi.nlm.nih.gov/pubmed/14699500