increased adenoma incidence_Nkx2-1<tm2Shk>/Nkx2-1<tm2Shk>,Tg(TPO-cre)1Shk/0

http://metadb.riken.jp/0010383I129X1SvJFVBNCrNkx21tm2ShkNkx21tm2ShkTgTPOcre1Shk0TgTPOcre1ShkNkx21tm2Shk

increased adenoma incidence_Nkx2-1<tm2Shk>/Nkx2-1<tm2Shk>,Tg(TPO-cre)1Shk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NK2 homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:108067
• transgene insertion 1, Shioko Kimura
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653643

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nkx2-1<tm2Shk>/Nkx2-1<tm2Shk>,Tg(TPO-cre)1Shk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TPO-cre)1Shk|Nkx2-1<tm2Shk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * FVB/NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased adenoma incidence
  http://purl.obolibrary.org/obo/MP_0010383

文献

http://purl.org/net/cito/citesAsAuthority

• Takashi. Kusakabe, et.al., Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid., Molecular endocrinology (Baltimore, Md.), 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16601074