ventricular septal defect_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0

http://metadb.riken.jp/0010402I129C57BL6SJLGtROSA26Sortm1Sho0Itga5tm2HynItga5tm1HynItgavtm2HynItgavTgTekcre1Ywa0Itga5tm1HynTgTekcre1YwaGtROSA26Sortm1ShoItga5tm2HynItgavItgavtm2Hyn

ventricular septal defect_Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin alpha V
  http://metadb.riken.jp/db/mgi_rdf/MGI:96608
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309
• integrin alpha 5 (fibronectin receptor alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96604

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Sho>/0,Itga5<tm2Hyn>/Itga5<tm1Hyn>,Itgav<tm2Hyn>/Itgav<+>,Tg(Tek-cre)1Ywa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itga5<tm1Hyn>|Tg(Tek-cre)1Ywa|Gt(ROSA)26Sor<tm1Sho>|Itga5<tm2Hyn>|Itgav<+>|Itgav<tm2Hyn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• ventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010402

文献

http://purl.org/net/cito/citesAsAuthority

• Arjan. van der Flier, et.al., Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20570943