ventricular septal defect_Fgf10<tm1Ska>/Fgf10<+>,Fgf8<tm1Moon>/Fgf8<tm1Moon>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

http://metadb.riken.jp/0010402IC57BL6NCrljCBAJNCrljFgf10tm1SkaFgf10Fgf8tm1MoonFgf8tm1MoonMesp1tm2creYsaMesp1Mesp1tm2creYsaFgf8tm1MoonFgf10Fgf10tm1SkaMesp1

ventricular septal defect_Fgf10<tm1Ska>/Fgf10<+>,Fgf8<tm1Moon>/Fgf8<tm1Moon>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mesoderm posterior 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107785
• fibroblast growth factor 10
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099809
• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf10<tm1Ska>/Fgf10<+>,Fgf8<tm1Moon>/Fgf8<tm1Moon>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mesp1<tm2(cre)Ysa>|Fgf8<tm1Moon>|Fgf10<+>|Fgf10<tm1Ska>|Mesp1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6NCrlj * CBA/JNCrlj

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• ventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010402

文献

http://purl.org/net/cito/citesAsAuthority

• Yusuke. Watanabe, et.al., Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries., Circulation research, 2010, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/20035084