bicuspid aortic valve_Fgf8<tm1Mrc>/Fgf8<tm1Moon>,Hoxa3<tm1(cre)Moon>/Hoxa3<+>

http://metadb.riken.jp/0010484I129SvC57BL6Fgf8tm1MrcFgf8tm1MoonHoxa3tm1creMoonHoxa3Fgf8tm1MoonHoxa3Fgf8tm1MrcHoxa3tm1creMoon

bicuspid aortic valve_Fgf8<tm1Mrc>/Fgf8<tm1Moon>,Hoxa3<tm1(cre)Moon>/Hoxa3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• homeobox A3
  http://metadb.riken.jp/db/mgi_rdf/MGI:96175
• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1Mrc>/Fgf8<tm1Moon>,Hoxa3<tm1(cre)Moon>/Hoxa3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgf8<tm1Moon>|Hoxa3<+>|Fgf8<tm1Mrc>|Hoxa3<tm1(cre)Moon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• bicuspid aortic valve
  http://purl.obolibrary.org/obo/MP_0010484

文献

http://purl.org/net/cito/citesAsAuthority

• Timothy L. Macatee, et.al., Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development., Development (Cambridge, England), 2003, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/14623825