atrioventricular block_Cacna1d<tm1Jst>/Cacna1d<tm1Jst>

http://metadb.riken.jp/0010519I129S7SvEvBrdC57BL6JCacna1dtm1JstCacna1dtm1JstCacna1dtm1Jst

atrioventricular block_Cacna1d<tm1Jst>/Cacna1d<tm1Jst>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, L type, alpha 1D subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:88293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1d<tm1Jst>/Cacna1d<tm1Jst>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cacna1d<tm1Jst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• atrioventricular block
  http://purl.obolibrary.org/obo/MP_0010519

文献

http://purl.org/net/cito/citesAsAuthority

• J. Platzer, et.al., Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels., Cell, 2000, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/10929716
• Pietro. Mesirca, et.al., G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block., Proceedings of the National Academy of Sciences of the United States of America, 2016, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/26831068