sinus bradycardia_Tbx3<tm2.1Moon>/Tbx3<tm2.1Moon>

http://metadb.riken.jp/0010637I129BALBcJC57BL6FVBNSJLTbx3tm21MoonTbx3tm21MoonTbx3tm21Moon

sinus bradycardia_Tbx3<tm2.1Moon>/Tbx3<tm2.1Moon>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T-box 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tbx3<tm2.1Moon>/Tbx3<tm2.1Moon>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tbx3<tm2.1Moon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/cJ * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• sinus bradycardia
  http://purl.obolibrary.org/obo/MP_0010637

文献

http://purl.org/net/cito/citesAsAuthority

• Deborah U. Frank, et.al., Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22203979