increased glioblastoma incidence_Gt(ROSA)26Sor<tm2Thl>/Gt(ROSA)26Sor<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tyr<c-Brd>/Tyr<c-Brd>

http://metadb.riken.jp/0010727I129Sv129S4SvJaeC57BL6GtROSA26Sortm2ThlGtROSA26SorPtentm1HwuPtentm1HwuTyrcBrdTyrcBrdTyrcBrdGtROSA26SorPtentm1HwuGtROSA26Sortm2Thl

increased glioblastoma incidence_Gt(ROSA)26Sor<tm2Thl>/Gt(ROSA)26Sor<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tyr<c-Brd>/Tyr<c-Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tyrosinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98880
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2Thl>/Gt(ROSA)26Sor<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tyr<c-Brd>/Tyr<c-Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tyr<c-Brd>|Gt(ROSA)26Sor<+>|Pten<tm1Hwu>|Gt(ROSA)26Sor<tm2Thl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased glioblastoma incidence
  http://purl.obolibrary.org/obo/MP_0010727

文献

http://purl.org/net/cito/citesAsAuthority

• Liang. Lei, et.al., Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21625383