abnormal NK cell physiology_Il12rb2<tm1Jm>/Il12rb2<tm1Jm>

http://metadb.riken.jp/0010766EI129S1SvBALBcByJorI129S1SvC57BL6JIl12rb2tm1JmIl12rb2tm1JmIl12rb2tm1Jm

abnormal NK cell physiology_Il12rb2<tm1Jm>/Il12rb2<tm1Jm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 12 receptor, beta 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270861

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il12rb2<tm1Jm>/Il12rb2<tm1Jm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il12rb2<tm1Jm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S1/Sv * BALB/cByJ) or (involves: 129S1/Sv * C57BL/6J)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal NK cell physiology
  http://purl.obolibrary.org/obo/MP_0010766

文献

http://purl.org/net/cito/citesAsAuthority

• C. Wu, et.al., IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites., Journal of immunology (Baltimore, Md. : 1950), 2000, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/11086056