abnormal NK cell physiology_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Sh2d1b1<tm3Vei>/Sh2d1b1<tm3Vei>

http://metadb.riken.jp/0010766I129S6SvEvTacC57BL6Sh2d1atm1PlsSh2d1atm1PlsSh2d1b1tm3VeiSh2d1b1tm3VeiSh2d1atm1PlsSh2d1b1tm3Vei

abnormal NK cell physiology_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Sh2d1b1<tm3Vei>/Sh2d1b1<tm3Vei>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1B1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349420
• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>,Sh2d1b1<tm3Vei>/Sh2d1b1<tm3Vei>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sh2d1a<tm1Pls>|Sh2d1b1<tm3Vei>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal NK cell physiology
  http://purl.obolibrary.org/obo/MP_0010766

文献

http://purl.org/net/cito/citesAsAuthority

• Zhongjun. Dong, et.al., The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells., Immunity, 2012, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/22683124