increased type II pneumocyte number_Itga3<tm1Hap>/Itga3<tm1Hap>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

http://metadb.riken.jp/0010810I129C57BL6Itga3tm1HapItga3tm1HapTgSFTPCrtTA5JawTgtetOcre1JawItga3tm1HapTgSFTPCrtTA5JawTgtetOcre1Jaw

increased type II pneumocyte number_Itga3<tm1Hap>/Itga3<tm1Hap>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584
• transgene insertion 5, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679530
• integrin alpha 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:96602

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itga3<tm1Hap>/Itga3<tm1Hap>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itga3<tm1Hap>|Tg(SFTPC-rtTA)5Jaw|Tg(tetO-cre)1Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased type II pneumocyte number
  http://purl.obolibrary.org/obo/MP_0010810

文献

http://purl.org/net/cito/citesAsAuthority

• Kevin K. Kim, et.al., Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19104148