decreased bone trabecula number_Bmp1<tm1Dgr>/Bmp1<tm1Dgr>,Tll1<tm2.1Dgr>/Tll1<tm2.1Dgr>,Tg(UBC-cre/ERT2)1Ejb/0

http://metadb.riken.jp/0010869I129SSvEv129S6SvEvTacC57BL6SJLBmp1tm1DgrBmp1tm1DgrTll1tm21DgrTll1tm21DgrTgUBCcreERT21Ejb0TgUBCcreERT21EjbBmp1tm1DgrTll1tm21Dgr

decreased bone trabecula number_Bmp1<tm1Dgr>/Bmp1<tm1Dgr>,Tll1<tm2.1Dgr>/Tll1<tm2.1Dgr>,Tg(UBC-cre/ERT2)1Ejb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tolloid-like
  http://metadb.riken.jp/db/mgi_rdf/MGI:106923
• bone morphogenetic protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88176
• transgene insertion 1, Eric J Brown
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707330

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmp1<tm1Dgr>/Bmp1<tm1Dgr>,Tll1<tm2.1Dgr>/Tll1<tm2.1Dgr>,Tg(UBC-cre/ERT2)1Ejb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(UBC-cre/ERT2)1Ejb|Bmp1<tm1Dgr>|Tll1<tm2.1Dgr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased bone trabecula number
  http://purl.obolibrary.org/obo/MP_0010869

文献

http://purl.org/net/cito/citesAsAuthority

• Alison M. Muir, et.al., Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice., Human molecular genetics, 2014, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/24419319