increased bone volume_Dkk1<tm1Lmgd>/Dkk1<+>,Kremen1<tm1Dgen>/Kremen1<tm1Dgen>,Kremen2<tm1Cni>/Kremen2<tm1Cni>

http://metadb.riken.jp/0010875EB6CgKremen1tm1DgenKremen2tm1CniDkk1tm1LmgdorI129S1Sv129X1SvJCD1Dkk1tm1LmgdDkk1Kremen1tm1DgenKremen1tm1DgenKremen2tm1CniKremen2tm1CniKremen2tm1CniKremen1tm1DgenDkk1tm1LmgdDkk1

increased bone volume_Dkk1<tm1Lmgd>/Dkk1<+>,Kremen1<tm1Dgen>/Kremen1<tm1Dgen>,Kremen2<tm1Cni>/Kremen2<tm1Cni>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• kringle containing transmembrane protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920266
• kringle containing transmembrane protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1933988
• dickkopf WNT signaling pathway inhibitor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1329040

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dkk1<tm1Lmgd>/Dkk1<+>,Kremen1<tm1Dgen>/Kremen1<tm1Dgen>,Kremen2<tm1Cni>/Kremen2<tm1Cni>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kremen2<tm1Cni>|Kremen1<tm1Dgen>|Dkk1<tm1Lmgd>|Dkk1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: B6.Cg-Kremen1<tm1Dgen> Kremen2<tm1Cni> Dkk1<tm1Lmgd> or (involves: 129S1/Sv * 129X1/SvJ * CD-1)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased bone volume
  http://purl.obolibrary.org/obo/MP_0010875

文献

http://purl.org/net/cito/citesAsAuthority

• Kristina. Ellwanger, et.al., Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18505822