lung epithelium hyperplasia_Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<+>

http://metadb.riken.jp/0010945I129S4SvJaeKrastm4TyjKrasScribtm11PhumScribScribtm11PhumKrastm4TyjKrasScrib

lung epithelium hyperplasia_Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• scribbled planar cell polarity
  http://metadb.riken.jp/db/mgi_rdf/MGI:2145950

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Scrib<tm1.1Phum>/Scrib<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scrib<tm1.1Phum>|Kras<tm4Tyj>|Kras<+>|Scrib<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• lung epithelium hyperplasia
  http://purl.obolibrary.org/obo/MP_0010945

文献

http://purl.org/net/cito/citesAsAuthority

• I A. Elsum, et.al., Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo., Oncogene, 2014, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/24276238