abnormal bronchial cartilage morphology_Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Twist2<tm1(cre)Dor>/Twist2<+>

http://metadb.riken.jp/0010988I129X1SvJC57BL6Tgfbr2tm12HlmTgfbr2tm12HlmTwist2tm1creDorTwist2Twist2Twist2tm1creDorTgfbr2tm12Hlm

abnormal bronchial cartilage morphology_Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Twist2<tm1(cre)Dor>/Twist2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• twist basic helix-loop-helix transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104685
• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>,Twist2<tm1(cre)Dor>/Twist2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Twist2<+>|Twist2<tm1(cre)Dor>|Tgfbr2<tm1.2Hlm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal bronchial cartilage morphology
  http://purl.obolibrary.org/obo/MP_0010988

文献

http://purl.org/net/cito/citesAsAuthority

• Min. Li, et.al., Mesodermal deletion of transforming growth factor-beta receptor II disrupts lung epithelial morphogenesis: cross-talk between TGF-beta and Sonic hedgehog pathways., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18990706