increased aorta wall thickness_Pdgfrb<tm13(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0010996I129S4SvJaeC57BL6CBAPdgfrbtm13PdgfrbSorPdgfrbTgSox2cre1Amc0PdgfrbPdgfrbtm13PdgfrbSorTgSox2cre1Amc

increased aorta wall thickness_Pdgfrb<tm13(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• platelet derived growth factor receptor, beta polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97531

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdgfrb<tm13(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdgfrb<+>|Pdgfrb<tm13(Pdgfrb)Sor>|Tg(Sox2-cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased aorta wall thickness
  http://purl.obolibrary.org/obo/MP_0010996

文献

http://purl.org/net/cito/citesAsAuthority

• Lorin E. Olson, et.al., PDGFRβ signaling regulates mural cell plasticity and inhibits fat development., Developmental cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21664579