abnormal branching involved in lung morphogenesis_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>

http://metadb.riken.jp/0011024I129C57BL6JDicer1tm1MmkDicer1tm1MmkShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDicer1tm1Mmk

abnormal branching involved in lung morphogenesis_Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Mmk>/Dicer1<tm1Mmk>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shh<+>|Shh<tm1(EGFP/cre)Cjt>|Dicer1<tm1Mmk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal branching involved in lung morphogenesis
  http://purl.obolibrary.org/obo/MP_0011024

文献

http://purl.org/net/cito/citesAsAuthority

• Yongjun. Yin, et.al., Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma., PLoS genetics, 2015, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/25978641