increased macrophage apoptosis_Trem2<em1Bwef>/Trem2<em1Bwef>

http://metadb.riken.jp/0011080IC57BL6JDBA2JFVBNTrem2em1BwefTrem2em1BwefTrem2em1Bwef

increased macrophage apoptosis_Trem2<em1Bwef>/Trem2<em1Bwef>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• triggering receptor expressed on myeloid cells 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913150

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trem2<em1Bwef>/Trem2<em1Bwef>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trem2<em1Bwef>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * DBA/2J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased macrophage apoptosis
  http://purl.obolibrary.org/obo/MP_0011080

文献

http://purl.org/net/cito/citesAsAuthority

• Gernot. Kleinberger, et.al., The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism., The EMBO journal, 2017, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/28559417