decreased macrophage apoptosis_Ticam1<Lps2>/Ticam1<Lps2>

http://metadb.riken.jp/0011081IC57BL6Ticam1Lps2Ticam1Lps2Ticam1Lps2

decreased macrophage apoptosis_Ticam1<Lps2>/Ticam1<Lps2>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• toll-like receptor adaptor molecule 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2147032

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ticam1<Lps2>/Ticam1<Lps2>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ticam1<Lps2>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased macrophage apoptosis
  http://purl.obolibrary.org/obo/MP_0011081

文献

http://purl.org/net/cito/citesAsAuthority

• K. Hoebe, et.al., Identification of Lps2 as a key transducer of MyD88-independent TIR signalling., Nature, 2003, 424
  http://rdf.ncbi.nlm.nih.gov/pubmed/12872135
• Klaus. Ruckdeschel, et.al., Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages., Journal of immunology (Baltimore, Md. : 1950), 2004, 173
  http://rdf.ncbi.nlm.nih.gov/pubmed/15322195