postnatal lethality, complete penetrance_Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Nkx2-5-cre)9Eno/0

http://metadb.riken.jp/0011085EI129S6SvEvTacBlackSwissorI129S6SvEvTacC57BL6Hand1tm1EnoHand1tm2EnoTgNkx25cre9Eno0Hand1tm1EnoTgNkx25cre9EnoHand1tm2Eno

postnatal lethality, complete penetrance_Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Nkx2-5-cre)9Eno/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• heart and neural crest derivatives expressed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103577
• transgene insertion 9, Eric N Olson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3514033

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Nkx2-5-cre)9Eno/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hand1<tm1Eno>|Tg(Nkx2-5-cre)9Eno|Hand1<tm2Eno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• David G. McFadden, et.al., The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner., Development (Cambridge, England), 2005, 132
  http://rdf.ncbi.nlm.nih.gov/pubmed/15576406