postnatal lethality, complete penetrance_Smn1<tm1Msd>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0,Tg(SMN2*delta7)4299Ahmb/0

http://metadb.riken.jp/0011085FVBCgGrm7TgSMN289AhmbSmn1tm1MsdTgSMN2delta74299AhmbSmn1tm1MsdSmn1tm1MsdGrm7TgSMN289Ahmb0TgSMN2delta74299Ahmb0Grm7TgSMN289AhmbSmn1tm1MsdTgSMN2delta74299Ahmb

postnatal lethality, complete penetrance_Smn1<tm1Msd>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0,Tg(SMN2*delta7)4299Ahmb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257
• transgene insertion 4299, Arthur H M Burghes
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056917
• glutamate receptor, metabotropic 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351344

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smn1<tm1Msd>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0,Tg(SMN2*delta7)4299Ahmb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grm7<Tg(SMN2)89Ahmb>|Smn1<tm1Msd>|Tg(SMN2*delta7)4299Ahmb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.Cg-Grm7<Tg(SMN2)89Ahmb> Smn1<tm1Msd> Tg(SMN2*delta7)4299Ahmb

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Thanh T. Le, et.al., SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN., Human molecular genetics, 2005, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/15703193