postnatal lethality, complete penetrance_Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0

http://metadb.riken.jp/0011085I129129P2OlaHsdFVBNOlig2tm1creTmjOlig2Smn1tm1JmeSmn1tm1MsdGrm7TgSMN289Ahmb0Smn1tm1MsdOlig2tm1creTmjGrm7TgSMN289AhmbOlig2Smn1tm1Jme

postnatal lethality, complete penetrance_Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, metabotropic 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351344
• oligodendrocyte transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355331
• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smn1<tm1Msd>|Olig2<tm1(cre)Tmj>|Grm7<Tg(SMN2)89Ahmb>|Olig2<+>|Smn1<tm1Jme>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Gyu-Hwan. Park, et.al., Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20826664