postnatal lethality, complete penetrance_Cacna1a<tm1Nobs>/Cacna1a<tm2Nobs>

http://metadb.riken.jp/0011085I129C57BL6JCacna1atm1NobsCacna1atm2NobsCacna1atm2NobsCacna1atm1Nobs

postnatal lethality, complete penetrance_Cacna1a<tm1Nobs>/Cacna1a<tm2Nobs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:109482

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1a<tm1Nobs>/Cacna1a<tm2Nobs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cacna1a<tm2Nobs>|Cacna1a<tm1Nobs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Hiromitsu. Saito, et.al., Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice., Biochemical and biophysical research communications, 2009, 390
  http://rdf.ncbi.nlm.nih.gov/pubmed/19854154