postnatal lethality, complete penetrance_Nlrp3<tm1Flv>/Nlrp3<tm1Hhf>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0011085I129C57BL6Nlrp3tm1FlvNlrp3tm1HhfLyz2tm1creIfoLyz2Nlrp3tm1HhfNlrp3tm1FlvLyz2tm1creIfoLyz2

postnatal lethality, complete penetrance_Nlrp3<tm1Flv>/Nlrp3<tm1Hhf>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897
• NLR family, pyrin domain containing 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653833

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nlrp3<tm1Flv>/Nlrp3<tm1Hhf>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nlrp3<tm1Hhf>|Nlrp3<tm1Flv>|Lyz2<tm1(cre)Ifo>|Lyz2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Susannah D. Brydges, et.al., Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19501000