postnatal lethality, complete penetrance_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0011085I129P2OlaHsd129SSvC57BL6JCBAJPbx1tm1KossPbx1tm1KossPbx2tm1MlcPbx2TgWnt1cre11Rth0TgWnt1cre11RthPbx2tm1MlcPbx1tm1KossPbx2

postnatal lethality, complete penetrance_Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pre B cell leukemia homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341793
• pre B cell leukemia homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97495
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pbx1<tm1Koss>/Pbx1<tm1Koss>,Pbx2<tm1Mlc>/Pbx2<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Pbx2<tm1Mlc>|Pbx1<tm1Koss>|Pbx2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Elisabetta. Ferretti, et.al., A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis., Developmental cell, 2011, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/21982646