postnatal lethality, complete penetrance_Glul<tm3Whla>/Glul<tm1Whla>,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0011085I129P2OlaHsdFVBNGlultm3WhlaGlultm1WhlaTgGFAPcre25Mes0TgGFAPcre25MesGlultm3WhlaGlultm1Whla

postnatal lethality, complete penetrance_Glul<tm3Whla>/Glul<tm1Whla>,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047
• glutamate-ammonia ligase (glutamine synthetase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95739

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Glul<tm3Whla>/Glul<tm1Whla>,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(GFAP-cre)25Mes|Glul<tm3Whla>|Glul<tm1Whla>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Youji. He, et.al., Glutamine synthetase deficiency in murine astrocytes results in neonatal death., Glia, 2010, 58
  http://rdf.ncbi.nlm.nih.gov/pubmed/20140959