postnatal lethality, complete penetrance_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?

http://metadb.riken.jp/0011085I129S1Sv129X1SvJC57BL6CBAAdartm11PhsAdartm2PhsTgMx1cre1CgnAdartm2PhsAdartm11PhsTgMx1cre1Cgn

postnatal lethality, complete penetrance_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• adenosine deaminase, RNA-specific
  http://metadb.riken.jp/db/mgi_rdf/MGI:1889575

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adar<tm2Phs>|Adar<tm1.1Phs>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Jochen C. Hartner, et.al., ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19060901